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I.R.C.V.
Institute of Cardiovascular Research
  • Dijon, Burgundy
  • France
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The technologies mastered in the Institute of Cardiovascular Research offer uniques opportunity of  fundamental, experimental and pre-clinical investigations in physiological as well as in controled patholoical conditions

Initially tailored for cells of cardiovascular origin, our methods can fit any kind of cells, such as cancer cell lines, nervous cells, ...
 
Pharmacology - Drug Testing

  • multiparametric phamacology of membrane receptors, ion channels and transporters
  • investigation of drugs acting on cellular metabolism, signaling
    and ultrastructure
  • extended cytotoxicity tests: anticancer drugs, immunosuppressors,
    and much more ...
 tx_ap


Ischemia-Reperfusion

  • functional and biological correlates of  the different components of ischemia and reperfusion, alone or in any combination
  • apoptosis messengery and regulation
  • cellular stress signaling
  • metabolic and gas dependence of reperfusion

 isch

Cardioprotection

  • substrate and gas dependence of reperfusion
  • thermal dependence of ischemia and reperfusion
  • hibernation signaling
  • in vitro cellular model of  heart graft preservation

 hsp

Free radicals
  • functional and biological effects of exogenous radical species
  • analysis of free radical production by the cells
  • free radical metabolism

 dhe



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